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Patients with renal artery stenosis short-term administration of valsartan diovan to twelve patients with renovascular hypertension secondary to unilateral renal artery stenosis did not induce any significant changes in renal hemodynamics, serum creatinine, or blood urea nitrogen bun .

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In multiple-dose studies in hypertensive patients with stable renal insufficiency and patients with renovascular hypertensionvalsartan had no clinically significant effects on glomerular filtration ratefiltration fractioncreatinine clearanceor renal plasma flow.

Valsartan is an angiotensin II receptor antagonistValsartan keeps blood vessels from narrowingwhich lowers blood pressure and improves blood flow.

Be careful drivingoperating machinery or doing jobs that require you to be alert while you are taking Diovan until you know how it affects you.

Use of drugs that act on the renin-angiotensin system during the second and third trimesters of pregnancy reduces fetal renal function and increases fetal and neonatal morbidity and deathResulting oligohydramnios can be associated with fetal lung hypoplasia and skeletal deformationsPotential neonatal adverse effects include skull hypoplasiaanuriahypotensionrenal failureand deathWhen pregnancy is detecteddiscontinue Diovan as soon as possiblesee Use In Specific Populations

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an increase in the incidence of dizziness was observed in patients treated with diovan 320 mg 8 compared to 10 to 160 mg 2 to 4 .