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In an era of increasing resistance to many antibacterial agents, chloramphenicol might have a role in the treatment of intra abdominal infections and respiratory tract infections caused by multi drug-resistant pathogens.

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although an inadequate therapeutic response has been reported after intramuscular administration, 21 more studies in enteric fever have suggested that peak plasma chloramphenicol concentrations are not influenced significantly by the route of parenteral administration.

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